05:35

our subject isn't cool, but he fakes it anyway
НЕ КЛАСТЬ В ХОЛОДИЛЬНИК

- помидоры
- базилик
- картофель
- чеснок
- лук
- авокадо
- оливковое масло
- хлеб
- кофе
- мед
- цитрусы
- маринованные огурцы
- травы
- салатные заправки
- кетчуп

@темы: nb

our subject isn't cool, but he fakes it anyway
Children deprived of loving care have reduced white matter in crucial parts of the brain compared to those raised in a better environment. The observations are not surprising in light of the well-known behavioral effects of neglect, but what this study has done is identify and measure the areas of the brain most affected.

The encouraging aspect of the study is that the damage may be reversible if children receive good care from 24 months; but even if this proves right, it is not clear how late is too late to prevent lifelong injury.

The Ceausescu government of Romania banned both contraception and abortion, leading to hundreds of thousands of abandoned children. Conditions in the institutions, wrongly called orphanages, in which they were kept were always awful, but became worse in the 1980s as the economy collapsed. After the fall of the regime international charities struggled to address the problem, although there remains debate as to how much conditions have improved.

In an attempt to salvage something from this horrifying humanitarian disaster, scientists and charities have been studying the effects on children. The institutions provided a chance to determine the effects on children raised in conditions where nutrition and shelter were (sometimes) adequate, but caretakers had no time to provide meaningful human interactions, even if they wanted to.

The Bucharest Early Intervention Project allocated a group of two year old children randomly, so that some remained in institutions while others were placed in foster care. Several rounds of studies have been done on these children, who are now in their late teens.

A paper in JAMA Pediatrics compares images of the brains of the children at the ages of two and eight, taken by diffusion tensor imaging, a form of MRI. The sample included 26 institutionalized children: 23 who were given foster care from 24 months and 20 from a control group of the local community.

Those who spent their childhoods in orphanages had significantly less developed white matter in at least four parts of the brain. Unsurprisingly, brain regions responsible for emotion are particularly heavily affected, but so are those associated with maintaining attention, executive function and even sensory processing.

The progress of the same children has also been studied in other ways, reaching similar conclusions.

At the age of eight, children who had once been in the orphanage but were then placed in foster care fell between the other two groups in the state of their white matter. The researchers concluded that their brains more closely resembled those of the children raised by their parents. However, a larger sample size is needed for confidence in this conclusion, and hopefully opportunities for further studies of this sort will be sparse.

The ethics of studying children raised in such conditions remain controversial, but with 8 million children worldwide living in institutions the significance is huge. Many charities are available for those wanting to make an immediate difference, both to assist in finding foster homes and to enable struggling parents to keep children.

@темы: yeah, science!, псих, ликвидация безграмотности

05:02

our subject isn't cool, but he fakes it anyway
our subject isn't cool, but he fakes it anyway
Britain moves closer to becoming the first country to allow 'three-parent babies' after historic vote
www.itv.com/news/2015-02-03/britain-could-becom...

MPs have paved the way for so-called 'three-parent babies' after an historic free vote in the House of Commons today.

They voted overwhelmingly in favour of reforming the 2008 Human Fertilisation and Embryology Act by 382 votes to 128.

If the House of Lords ratifies the decision, the UK will become the first country to allow mitochondrial donation.

This controversial technique involves conceiving IVF babies with DNA from three different people to avoid devastating inherited diseases.

ITV News Health Editor Rachel Younger reports:
IVF_YoungernewPlay video
Pro-life groups and some Church leaders opposed the change on ethical and safety grounds.

But the Prime Minister, speaking shortly before the vote, insisted there was no question of "playing God".

David Cameron said: "As someone who had a severely disabled child himself, I know what parents go through when they are concerned about these issues.

"If science can help in this way, and I think all the arguments are in favour, we should make sure these new treatments are available."

Labour leader Ed Miliband and Deputy Prime Minister Nick Clegg also exercised their free vote to support the decision.
Nurse: 'Vote could determine my chance of healthy kids'
MPs vote on whether to amend the 2008 Human Fertilisation and Embryology Act
MPs vote on whether to amend the 2008 Human Fertilisation and Embryology Act
Under the new technique, IVF babies would still inherit the vast majority of their DNA - which determines individual traits such as facial features and personality - from their two parents.

A tiny amount of mitochondrial DNA would be donated from an anonymous woman donor.

Mitochondrial DNA makes up just 0.1% of a person's genetic code, but faults can lead to a wide range of devastating and sometimes life-threatening inherited diseases.

It can be responsible for conditions including blindness, deafness, muscle wasting, diabetes, heart failure and dementia.
Read: How does 'three-parent' IVF work?
Under the technique, IVF babies could be conceived with DNA from three people.
Under the technique, IVF babies could be conceived with DNA from three people. Credit: ITV News
Scientists led by Professor Doug Turnbull at the Wellcome Trust Centre for Mitochondrial Research at Newcastle University have pioneered the technique and hope to be the first to offer the treatment.

читать дальше

@темы: yeah, science!

our subject isn't cool, but he fakes it anyway
Jetting half way across the world, shift work and those crazy all-nighters are all things that can upset our body’s daily cycle, or circadian rhythm. Over the years, scientists have slowly been piecing together the components of our “biological clocks” that drive these rhythms, and we now have a pretty good understanding of how they are coordinated. Now, scientists have discovered what is effectively a “reset button” in mice, which could eventually help researchers develop novel treatments that correct mismatches between the environment and our internal body clocks.

Circadian rhythms are physiological, mental and behavioral changes that follow an approximately 24-hour cycle, which are primarily dictated by changes in light in the environment. These oscillations are driven by groups of interacting molecules in the body which are collectively known as biological clocks, and it is the job of a master pacemaker located in the brain to coordinate and regulate these clocks to make sure the body is in sync.

It’s been known for some time that this “master clock” is a bundle of neurons in a region called the suprachaismatic nucleus (SCN); however, scientists didn’t know whether altering the way that these cells fire could change how it operates. Now, researchers from Vanderbilt University have demonstrated that it is indeed possible to control the clock by selectively switching on and off this population of cells, which effectively mimics their daytime and nighttime activity.

In order to manipulate the activity of these neurons, the researchers used a sophisticated technique known as optogenetics. This involves inserting genes that code for light-sensitive proteins into distinct populations of cells, creating a bundle of neurons that now respond to light in a certain way. Then, after implanting an optical fiber into the brain, scientists can use lasers to either stimulate (switch on) or inhibit (switch off) these cells.

As described in Nature Neuroscience, the researchers found that by artificially stimulating the SCN neurons, they were able to manipulate the mouse’s sleep/wake rhythms, effectively resetting the master clock. This was particularly interesting because previous work suggested that the firing activity of these cells was only an output of the clock’s activity.

“Of course, this exact approach isn’t ready for human use yet,” said study author Michael Tackenberg. “But others are making progress toward eventually using optogenetics as therapy.” Tackenberg is now taking the work forward by examining whether mice suffering from seasonal affective disorder—a type of depression that has a seasonal pattern—respond to the stimulation.

@темы: социальное, мотивировочная часть, yeah, science!, псих, ликвидация безграмотности

03:59

our subject isn't cool, but he fakes it anyway


прекрасная штука: billboard.fm/birthday-song
у меня u2 - with or without you
выложила папину
эта итальянская попса излучает какую-то нескончаемую радость от жизни

@темы: music, шоб позырить, that's my jam

our subject isn't cool, but he fakes it anyway
На улице — дождик и слякоть,
Не знаешь, о чем горевать.
И скучно, и хочется плакать,
И некуда силы девать.

Глухая тоска без причины
И дум неотвязный угар.
Давай-ка наколем лучины,
Раздуем себе самовар!

Авось, хоть за чайным похмельем
Ворчливые речи мои
Затеплят случайным весельем
Сонливые очи твои.

За верность старинному чину!
За то, чтобы жить не спеша!
Авось, и распарит кручину
Хлебнувшая чаю душа!

@темы: poetry

our subject isn't cool, but he fakes it anyway
Болото — глубокая впадина
Огромного ока земли.
Он плакал так долго,
Что в слезах изошло его око
И чахлой травой поросло.
Но сквозь травы и злаки
И белый пух смежённых ресниц —
Пробегает зеленая искра,
Чтобы снова погаснуть в болоте.
И тогда говорят в деревнях
Неизвестно откуда пришедшие
Колдуны и косматые ведьмы:
«Это шутит над вами болото.
Это манит вас темная сила».
И когда они так говорят,
Старики осеняются знаменьем крестным,
Пожидые — смеются,
А у девушек — ясно видны
За плечами белые крылья.

А. Блок

@темы: poetry

00:58

our subject isn't cool, but he fakes it anyway
00:54

our subject isn't cool, but he fakes it anyway
03:35

our subject isn't cool, but he fakes it anyway
я не могу пробиться в свой старый формспринг new.spring.me/#!/user/jelliclekitten не могу восстановить парол
у кого-нибудь бывает ощущение невероятного жизненного провала, когда вы видите безвозвратно упущенную возможность остроумно ответить на вопрос?
ask.fm/jellicle_kitten

омг иногда с видео отвечаю

@темы: мгимо финишд? - ааск!

05:39

our subject isn't cool, but he fakes it anyway


это одна из лучших речей на свете
как человек, испытывающий религиозно-наркоманский восторг от природы, но при этом агрессивный атеист, очень поддерживаю.

@темы: шоб позырить, there's no one out there, yeah, science!

05:18

our subject isn't cool, but he fakes it anyway
стихам дорогу!

poet Emily Jane Brontë

Love and Friendship



Love is like the wild rose-briar,
Friendship like the holly-tree --
The holly is dark when the rose-briar blooms
But which will bloom most contantly?
The wild-rose briar is sweet in the spring,
Its summer blossoms scent the air;
Yet wait till winter comes again
And who wil call the wild-briar fair?
Then scorn the silly rose-wreath now
And deck thee with the holly's sheen,
That when December blights thy brow
He may still leave thy garland green.

***

Отрывок из Friendship by Henry David Thoreau

Two sturdy oaks I mean, which side by side,
Withstand the winter's storm,
And spite of wind and tide,
Grow up the meadow's pride,
For both are strong

Above they barely touch, but undermined
Down to their deepest source,
Admiring you shall find
Their roots are intertwined
Insep'rably.

@темы: poetry, quotes

04:46

our subject isn't cool, but he fakes it anyway
Отрывок из книги "Токсичные родители".
Созависимость, преждевременное взросление, невидимый ребенок.
читать дальше

@темы: quotes, псих

03:57

our subject isn't cool, but he fakes it anyway
по-моему, я совершенно случайно нашла таки свой тип по mbti

Introverted Sensing Feeling Perceiving


то что никто не прочитает \ рус

В нашей соционике это Дюма.
Обычно мои варианты где-то между Лондоном и Есениным.
Странная это штука - соционика.

@темы: псих

19:10

our subject isn't cool, but he fakes it anyway
02:43

our subject isn't cool, but he fakes it anyway
04:46

our subject isn't cool, but he fakes it anyway
01:57

our subject isn't cool, but he fakes it anyway
У меня периодически случаются приступы любви к поэзии, так что выложу уже всеми сто раз процитированного Фроста оптом.
Без названий, потому что я вредная.

Here come real stars to fill the upper skies,
And here on earth come emulating flies,
That though they never equal stars in size,
(And they were never really stars at heart)
Achieve at times a very star-like start.
Only, of course, they can't sustain the part.

читать дальше
Nature's first green is gold,
Her hardest hue to hold.
Her early leaf's a flower;
But only so an hour.
Then leaf subsides to leaf.
So Eden sank to grief,
So dawn goes down to day.
Nothing gold can stay.

всем привет!



@темы: poetry, quotes

23:05

our subject isn't cool, but he fakes it anyway
озерный край

I wander'd lonely as a cloud
That floats on high o'er vales and hills,
When all at once I saw a crowd,
A host, of golden daffodils;
Beside the lake, beneath the trees,
Fluttering and dancing in the breeze.

Continuous as the stars that shine
And twinkle on the Milky Way,
They stretch'd in never-ending line
Along the margin of a bay:
Ten thousand saw I at a glance,
Tossing their heads in sprightly dance.

The waves beside them danced; but they
Out-did the sparkling waves in glee:
A poet could not but be gay,
In such a jocund company:
I gazed - and gazed - but little thought
What wealth the show to me had brought:

For oft, when on my couch I lie
In vacant or in pensive mood,
They flash upon that inward eye
Which is the bliss of solitude;
And then my heart with pleasure fills,
And dances with the daffodils.

@темы: poetry, quotes, фотография, lake district, uk